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New Program: Neonatal Thyroid Physiology
Neonatal Resuscitation - Minimally Invasive Approach
Use of an Entirely Human Milk-Based Diet in Very Low Birth Weight Infants
New Directions in Neonatal Respiratory Critical Care
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Latest Education
Non-Invasive Positive Pressure Ventilation - Evidence Base in Preterm Infants (Module 6 of 6)
Haresh Kirpalani, BM, MRCP, FRCP, MSc
Date Posted: 01/28/2014
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Neonatal Thyroid Physiology
Shazia Bhat, MD
Date Posted: 12/24/2014
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New Directions in Neonatal Respiratory Critical Care
Martin Keszler, MD; Thomas H. Shaffer, MS.E., PhD; Jan Mazela, MD, PhD
Date Posted: 01/05/2015
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Use of an Entirely Human Milk-Based Diet in VLBW Infants: Review of Current Evidence and Future Directions
Steven A. Abrams, MD, Professor of Pediatrics, Baylor College of Medicine
Date Posted: 11/06/2014
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Oxygen: Friend or Foe
Jonathan Davis, MD
Date Posted: October 15, 2014
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What many people may not know is part of the comprehensive care for the tiniest babies includes medications such as Sildenafil and caffeine. Nearly all of the babies in Nationwide Children’s Hospital’s neonatal intensive care units (NICUs) receive caffeine as they are coming off a ventilator and learning to breathe on their own.

Several new technologies being used in the Cedars-Sinai Neonatal Intensive Care Unit, part of the Maxine Dunitz Children’s Health Center, are helping our smallest babies with more rapid and healthier weight gain.

Newborns with significant jaundice are not likely to develop kernicterus if American Academy of Pediatrics' treatment guidelines are followed, according to a new study published online January 5 in JAMA Pediatrics.

In the largest study of its kind, researchers found that late CUS and near-term brain MRI were independently associated with neurodevelopmental impairment (NDI), independent of early CUS findings and other perinatal or neonatal factors.

Among full-term newborns with moderate or severe hypoxic ischemic encephalopathy (damage to cells in the central nervous system from inadequate oxygen), receiving deeper or longer duration cooling did not reduce risk of neonatal intensive care unit death, compared to usual care, according to a study in the December 24/31 issue of JAMA.

Late-onset sepsis (LOS) is a leading cause of illness and death in preterm newborns, and better diagnostic tools are needed. P-SEP, a trunked portion of soluble CD14, is released by various immune cells including macrophages, monocytes, and neutrophils, when stimulated by pathogens. P-SEP has recently been shown to be a reliable diagnostic and prognostic marker of sepsis in adults

"Infants who survived after treatment-limitation discussions usually did so because of decisions by their parents to continue intensive medical treatment," Dr. Dominic Wilkinson, a neonatal intensive care physician and director of Medical Ethics at the Oxford Uehiro Centre for Practical Ethics in the UK, told Reuters Health by email

We believe that we limit the amount of oxygen toxicity and free radical production by keeping oxygen saturations in the small babies between 88% and 92%. But if you walk the wards in the middle of the night, you will see that a lot of the nursing care is performed using 100% oxygen. That is something that we have been quite successful in eliminating, and it does make a big difference to the production of chronic lung disease–associated pulmonary hypertension.

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